With bright eyes and contagious enthusiasm, he eloquently shared his audacious dream of revitalizing the factory and reintroducing phage therapy to the world. His profound knowledge of bacteriophages and his unparalleled potential to revolutionize healthcare left us in awe and inspired to be part of this transformative journey. Bacteriophages (from the Greek for bacteria-eaters) or simply phages are the natural enemies of bacteria. They are strictly specific, e.g. Staphylococcus bacteriophage can only eliminate Staphylococcus bacteria, while Salmonella bacterium can only be targeted by its specific Salmonella bacteriophage, etc. Hundred times smaller than bacteria, phages are the most abundant microorganisms on earth and they are present everywhere (water, soil). A single drop of seawater can contain millions of phages, while the human body contains billions of them. Specially selected phages can very effectively eliminate even antibiotic-resistant bacteria (MRSA, Pseudomonas aeruginosa, Acinetobacter baumannii, E. coli, Enterobacteriaceae, Klebsiella, etc.) without harming anything else, thus ensuring unprecedented levels of safety for any antimicrobial solution. Here’s a short animated video to demonstrate how phages work.
Based on the world’s oldest factory (1934) that is fully dedicated to the production of phage medications, Rati’s team utilizes a paradigm shifting technology platform that effectively and sustainably replaces antibiotics in both the human and animal health industries. In human health, phage-based novel antibiotics are used to treat and prevent antibiotics resistant infections. Furthermore, the company employs the same sustainable technology to replace the irrational use of antibiotics in livestock production, which is the primary cause behind the development of antibiotic resistance.
Reviving a Soviet phage factory was no simple feat. The entrepreneur faced an array of challenges, from securing funding for the ambitious project to navigating complex regulatory landscapes. However, the entrepreneurial spirit backed with a multidisciplinary team of professionals from science, business and technology fueled his determination to overcome these hurdles. He was supported by the EU, the European Bank for Reconstruction and Development (EBRD), Food and Agriculture Organization of the United Nations (FAO), and Georgia’s Innovation and Technology Agency (GITA).